OpenAI Assistants API

Framework for LLM applications

The most widely-used framework for building LLM-powered applications, available in Python and JavaScript. Provides abstractions for chains, agents, RAG, memory, tool usage, and structured output. Integrates with 100+ LLM providers, vector stores, document loaders, and tools. LangSmith offers tracing and evaluation. LangGraph enables stateful, multi-agent workflows with cycles. 100K+ GitHub stars. The de facto standard for LLM application development despite growing alternatives like LlamaIndex.

Data framework for LLM applications

Leading Python framework for building LLM-powered applications with focus on data-aware and agentic workflows. Provides tools for RAG (Retrieval-Augmented Generation), document indexing, vector store integrations, query engines, and multi-agent orchestration. 150+ data connectors for various sources. Works with OpenAI, Anthropic, local models, and more. Includes LlamaHub for community tools and LlamaCloud for managed RAG pipelines. 50K+ GitHub stars.

Build AI-powered web apps

Open-source TypeScript toolkit by Vercel for building AI-powered apps with streaming chat UIs, structured outputs, tool calling, and agent workflows. Framework-agnostic core with integrations for React, Next.js, Svelte, Vue, and Nuxt. Supports a broad AI SDK v6 provider catalog including OpenAI, Anthropic, Google, xAI, Mistral, Bedrock, Groq, and OpenAI-compatible providers. Includes useChat and useCompletion hooks for rapid UI development. The standard SDK for adding AI features to web apps.

Open standard for portable skills across AI agents

Agent Skills is the open SKILL.md folder specification for packaging reusable instructions, scripts, references, and assets that compatible AI agents load through progressive disclosure. Originally developed by Anthropic and released as an open standard, it defines the portable format itself—not an example library, marketplace, or hosted agent product.

Open-source natural-language browser automation framework for AI agents

An AGPL-3.0 TypeScript framework that drives a real browser from natural-language tasks — the self-hostable OSS framework from Hyperbrowser, distinct from the vendor's paid cloud browser product.

JavaScript framework for building and visualizing multi-agent workflows on a Kanban board

KaibanJS is an MIT-licensed JavaScript framework for defining AI agents, tasks, tools, and teams, then orchestrating their work through a Kanban-inspired runtime and visual board. It can run inside Node.js, React, or Next.js projects, supports custom UIs and headless workflows, and provides real-time task-state visibility for multi-agent applications.

Multi-agent model API that orchestrates frontier models behind one OpenAI-compatible endpoint

Sakana Fugu is a hosted model-provider API that exposes a learned multi-agent system as one OpenAI-compatible model. It dynamically routes coding, code review, research, and reasoning tasks across a frontier-model pool, with Fugu for lower-latency work and Fugu Ultra for harder workloads where answer quality matters more than cost or speed.

LangChain CLI for maintaining agent-friendly codebase documentation

OpenWiki is LangChain’s open-source CLI for generating and maintaining an agent-focused wiki inside a codebase. It can create an openwiki/ documentation folder, update it from repository changes, add guidance to AGENTS.md or CLAUDE.md, and run via an interactive CLI or daily GitHub Action so coding agents have durable context without stuffing every detail into prompts.

Open-source desktop AI coworker for browsing and code execution.

Accomplish Coworker is an MIT-licensed open-source AI coworker that runs on the desktop, combining computer-use style browsing with code execution so agents can research, implement, run, and debug workflows in one local environment.