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Multi-agent AI framework

Python framework for orchestrating autonomous AI agents that collaborate to accomplish complex tasks. Define agents with specific roles, goals, and backstories, then organize them into crews with sequential or parallel task execution. Supports tool usage (web search, file I/O, API calls), memory, delegation between agents, and human-in-the-loop input. Works with OpenAI, Anthropic, local models, and more. 25K+ GitHub stars. Leading multi-agent framework alongside LangGraph and AutoGen.

Python agent framework by Pydantic team

Agent framework built on Pydantic for type-safe AI applications. Provides structured outputs, dependency injection, and multi-model support. Created by the Pydantic team, it brings the same validation and typing philosophy that made Pydantic essential for Python APIs to the world of AI agents, ensuring reliable data flow between LLMs and application logic.

Framework for LLM applications

The most widely-used framework for building LLM-powered applications, available in Python and JavaScript. Provides abstractions for chains, agents, RAG, memory, tool usage, and structured output. Integrates with 100+ LLM providers, vector stores, document loaders, and tools. LangSmith offers tracing and evaluation. LangGraph enables stateful, multi-agent workflows with cycles. 100K+ GitHub stars. The de facto standard for LLM application development despite growing alternatives like LlamaIndex.

Open standard for portable skills across AI agents

Agent Skills is the open SKILL.md folder specification for packaging reusable instructions, scripts, references, and assets that compatible AI agents load through progressive disclosure. Originally developed by Anthropic and released as an open standard, it defines the portable format itself—not an example library, marketplace, or hosted agent product.

Open-source natural-language browser automation framework for AI agents

An AGPL-3.0 TypeScript framework that drives a real browser from natural-language tasks — the self-hostable OSS framework from Hyperbrowser, distinct from the vendor's paid cloud browser product.

JavaScript framework for building and visualizing multi-agent workflows on a Kanban board

KaibanJS is an MIT-licensed JavaScript framework for defining AI agents, tasks, tools, and teams, then orchestrating their work through a Kanban-inspired runtime and visual board. It can run inside Node.js, React, or Next.js projects, supports custom UIs and headless workflows, and provides real-time task-state visibility for multi-agent applications.

Multi-agent model API that orchestrates frontier models behind one OpenAI-compatible endpoint

Sakana Fugu is a hosted model-provider API that exposes a learned multi-agent system as one OpenAI-compatible model. It dynamically routes coding, code review, research, and reasoning tasks across a frontier-model pool, with Fugu for lower-latency work and Fugu Ultra for harder workloads where answer quality matters more than cost or speed.

LangChain CLI for maintaining agent-friendly codebase documentation

OpenWiki is LangChain’s open-source CLI for generating and maintaining an agent-focused wiki inside a codebase. It can create an openwiki/ documentation folder, update it from repository changes, add guidance to AGENTS.md or CLAUDE.md, and run via an interactive CLI or daily GitHub Action so coding agents have durable context without stuffing every detail into prompts.

Open-source desktop AI coworker for browsing and code execution.

Accomplish Coworker is an MIT-licensed open-source AI coworker that runs on the desktop, combining computer-use style browsing with code execution so agents can research, implement, run, and debug workflows in one local environment.