Best AG2 Alternatives

AutoGen is an open-source programming framework from Microsoft Research for building AI agents and facilitating cooperation among multiple agents to solve complex tasks through multi-turn conversations. Pioneered conversable agents that interact, use tools, and involve humans in the loop for multi-agent workflows. v0.4 features a redesigned async event-driven architecture with stronger observability, flexible collaboration patterns, and reusable components.

Python framework for orchestrating autonomous AI agents that collaborate to accomplish complex tasks. Define agents with specific roles, goals, and backstories, then organize them into crews with sequential or parallel task execution. Supports tool usage (web search, file I/O, API calls), memory, delegation between agents, and human-in-the-loop input. Works with OpenAI, Anthropic, local models, and more. 25K+ GitHub stars. Leading multi-agent framework alongside LangGraph and AutoGen.

The most widely-used framework for building LLM-powered applications, available in Python and JavaScript. Provides abstractions for chains, agents, RAG, memory, tool usage, and structured output. Integrates with 100+ LLM providers, vector stores, document loaders, and tools. LangSmith offers tracing and evaluation. LangGraph enables stateful, multi-agent workflows with cycles. 100K+ GitHub stars. The de facto standard for LLM application development despite growing alternatives like LlamaIndex.